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DOI:
Emotional disorder and related factors in patients with Meige syndrome
LONG Yu-zhou,LEI Jin,CHEN Yang
()
Abstract:
Objective To study the incidence of depression in Meige syndrome and associated factors. Methods Sixty-two Meige syndrome patients with depression and 40 healthy subjects as control were evaluated using Hamilton Depression Scale(HAMD). Results Fifty-four point eight percent(34/ 62) of Meige syndrome pailents and 10% (4/40)of healthy subjects were found to have depression (H AMD score 8 or higher), 48.3% (30/62)of Meige syndrome patients and 7.5%(3/40) of healthy subjects had mild depression(HAMD score between 8 and 20), 6.5 % (4/62)of Meige syndrome patients and 2.5% (1/40) of healthy subjects were classified into moderately depressed range( HAMD score between 21 and 35). There were statistical differences in Meige syndrome group and healthy subjects group( χ2=20.91 ,P -C 0. 001). There was not statistical difference in severity. Additionally, there were statistical differences in anxiety/somatization, cognitive impairment, block, sleep disorder and despair between depression group and non--depression group. Conclusions The incidence of depression is higher in Meige syndrome. Manifestation of depression are anxiety, reduced interest in work, sleep disorders, retardedness,inferiority complex, etc. We found no evidence for an association of the depression with disease course in patients with Meige syndrome, but it is related to sex,easy to occur in females.
Key words:  Meige syndrome  Depression  HAMD

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